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婦科病理

乳癌

CA15-3 CA 19-9 CK 5 CK 7 CK 20 ER/PR p63 CD117
Infiltrating Ductal Carcinoma + + +
Adenoid Cystic Carcinoma + + + + + +

子宮頸癌

BCL2 CK 17 Ki-67 MCM3
Cervical Intraepithelial Neoplasia + +
Tubo-Endometrial Metaplasia + +
Microglandular Hyperplasia

宮頸上皮內瘤樣病變

CK 8 CK 17 p16
CIN I -/+ -/+ +
CIN II -/+ + +
CIN III + + +

卵巢癌

CA-125 CEA PAX-8 WT1
Ovarian CA, Serous + + + +
Ovarian CA, Mucinous
Ovarian CA, Endometrioid + +
Ovarian CA, Clear Cell + +

胎盤營養膜細胞

1st Trimester 2nd Trimester 3rd Trimester
hCG hPL hCG hPL hCG hPL
Cytotrophoblast
Intermediate Trophoblast 1-24% 25-49% -/+ 50-74% 1-24% 1-49%
Syncytiotrophoblast >75% 1-24% 25-49% 50-74% 1-24% >75%

胎盤營養膜增殖

CK
OSCAR
hCG hPL p57 PLAP Vimentin
Partial Mole + -/+ -/+ + +
Complete Mole + + -/+ -/+
Choriocarcinoma + + -/+ -/+ -/+
Placental Site Tumor +  +/- + + + +

性索間質腫瘤

Calretinin CD99 CK 7 EMA Inhibin MART-1 Vimentin
Granulosa Cell Tumors + + + + +
Sertoli-Leydig Cell Tumors + + + + + +
Gynandroblastoma + -/+ + +
Gonadoblastomas + + + +

子宮: 營養膜增殖

CK Cocktail hCG hPL p57 PLAP Vimentin
Partial Mole Strong, difuse Weak, difuse Weak, difuse + +
Complete Mole Strong, difuse Strong, difuse Weak, focal Weak, focal
Choriocarcinoma Strong, difuse Strong, difuse Weak, focal Weak, focal -/+
Placental Site Tumor Strong, difuse Strong, focal Strong, difuse Strong, difuse Strong, difuse

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皮膚病理

皮膚腫瘤

AR BCL2 CD10 CD34 CK 15 CK 19 CK 20 Ber-EP4
Basal Cell Carcinoma + + + + +
Trichoepithelioma + + + + + +
Merkel Cell Carcinoma + + + +
Microcystic Adnexal Carcinoma +  +/- + + -/+
Sebaceous Carcinoma + -/+  +/- +
Sebaceous Adenoma + + +

黑色素瘤

Nestin SOX-10 HMB-45 S-100
Desmoplastic Melanoma + + +
Conventional Melanoma + + + +

默克細胞癌 vs 皮膚小細胞腫瘤腫瘍

CD117 CK
Cocktail
CK 5&6 CK 20 Vimentin Chromogranin
A
Merkel Cell Carcinoma + + + +
Small Cell Carcinoma  +/- + +
Lymphoma  +/-
Small Cell Melanoma + +
Squamous Cell Carcinoma + +

默克細胞癌 vs 皮膚小細胞腫瘤 (part two)

HMB-45 Neurofilament Synaptophysin TTF-1 CD45 S-100
Merkel Cell Carcinoma + +
Small Cell Carcinoma + +
Lymphoma +
Small Cell Melanoma + +
Squamous Cell Carcinoma

皮膚附屬器腫瘤

CD15 CK 7 CK 20 EMA BRST-2 S-100
Merkel Cell Carcinoma + +
Sebaceous Tumor + +
Apocrine Tumor  +/- +  +/- +
Eccrine Tumor + + +

皮膚:基底細胞癌 VS 扁平上皮細胞癌

BCL2 CK
8&18
CK
Cocktail
EMA Ep-CAM MOC-31 UEA-1
Basal Cell Carcinoma + -/+ + + +
Squamous Cell Carcinoma + + +

皮膚:隆凸性皮膚纖維肉瘤(Dermatofibrosarcoma protuberans) vs Dermatofibroma Fibrous Histiocytoma

CD10 CD34 CD163 CK
Cocktail
Desmin Factor
XIIIa
NGFR p63 S-100
DF-SP  +/- + +
DF-FH + +

皮膚:帕哲氏(pagetoid)腫瘤

CEA CK,
HMW
CK,
LMW
S-100 Vimentin
Melanoma + +
Paget’s Disease + + -/+
Bowen’s Disease + +

紡錘細胞腫瘤

MS
Actin
SM
Actin
ALDH1A1 BG8 CD10 CD31 CD34 CD99 Collagen
IV
CK
8&18
Angiosarcoma + +
Atypical Fibroxanthomas + + + + +
Dermato broma Fibrous Histiocytoma +
Dermatofibrosarcoma Protuberans  +/- +
DF-FH +
DF-SP  +/- +
Glomus Tumor + +  +/- +
Hemangioma + + + + +
Hemangiopericytoma + + +
Kaposi’s Sarcoma + + +  +/-
Kaposiform Hemangioendothelioma + +
Peripheral Nerve Sheath + + + +
Smooth Muscle + + + -/+
Solitary Fibrous Tumor + +  +/-
Spindle Cell Melanoma
Spindle Squamous Cell Carcinoma +
Squamous Cell Carcinoma

紡錘細胞腫瘤 (part two)

CK
Cocktail
Factor
VIII
Factor
XIIIa
FLI-1 HHV-8 NGFR D2-40 S-100 STAT6
Angiosarcoma + +  +/-
Atypical Fibroxanthomas  +/- +
Dermato broma Fibrous Histiocytoma +
Dermatofibrosarcoma Protuberans +
DF-FH +
DF-SP +
Glomus Tumor
Hemangioma + +
Hemangiopericytoma + +
Kaposi’s Sarcoma +  +/- + + +
Kaposiform Hemangioendothelioma +
Peripheral Nerve Sheath + +  +/-
Smooth Muscle
Solitary Fibrous Tumor -/+
Spindle Cell Melanoma + + + +
Spindle Squamous Cell Carcinoma + +
Squamous Cell Carcinoma +

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腸胃病理

壺腹癌

CDX-2 MUC2 CK 17 MUC1
Intestinal Subtype + +
Ductal + +

胃腸道基質腫瘤(GIST)

CD34 CD117 DOG1
GIST, Kit Mutation + + +
GIST, PDGFRA Mutation +
GIST, Wild Type  +/- + +

脾臟/脾臟腫瘤

 β-Catenin CA 19-9 D10 CD56 CDX-2 Synaptophysin CK 7 CK 19 E-cadherin
Ductal Adenocarcinoma / Ductal Carcinoma  +/- +  +/- +  +/-
Pancreatic Adenocarcinoma +  +/- +
Pancreatic Endocrine Tumor +
Acinar Cell Carcinoma + -/+  +/- + +
Pancreatoblastoma + + +
Neuroendocrine Tumor +  +/- + +  +/-
Solid Pseudopapillary Tumor + + +  +(核)
Islet Cells + + +
Pancreatic Ducts +

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泌尿生殖器病理

膀胱組織

SM
Actin
MS
Actin
Calponin Smoothelin
Muscularis Mucosae + + +
Muscularis Propria + + + +

膀胱:形成異常 vs 反應性

CD44 CK 20 CK 5&6 Ki-67 MCM3 p53
Carcinoma-in-situ + + + +
Reactive Atypia + + + +
Normal Urothelium + + -/+ -/+ -/+

泌尿生殖器癌

CD10 CD117 CK 7 CK, HMW Ksp-cadherin RCC S100P TFE3
Xp11 Tr RCC + -/+ + + +
Clear Cell RCC + -/+ -/+ +
Papillary RCC + +  +/- -/+ +
Chromophobe RCC  +/- + + + +
Oncocytoma + + -/+ -/+ +
Urothelial Carcinoma +  +/- +  +/- +

胚細胞腫瘤

AFP CD30 CD117 CK
Cocktail
EMA GPC-3 hCG hPL Inhibin
Seminoma (Seminoma/Dysgerminoma) +
Embryonal Carcinoma + +
Choriocarcinoma + + + + +
Yolk Sac Tumor + -/+ + +
Granulosa Cell Tumor +
Hypercalcaemic Small Cell Carcinoma + +
Mature Teratoma  +/- + + -/+
Immature Teratoma  +/- + +  +/- -/+
Carcinoid +

胚細胞腫瘤 (part two)

Oct‐4 PLAP D2-40 SALL4 SOX-2 Synaptophysin Vimentin
Seminoma (Seminoma/Dysgerminoma) + + + + +
Embryonal Carcinoma + + + +
Choriocarcinoma + -/+
Yolk Sac Tumor -/+ +
Granulosa Cell Tumor  +/- +
Hypercalcaemic Small Cell Carcinoma +
Mature Teratoma  +/-  +/- +
Immature Teratoma  +/- + +
Carcinoid + +

生殖腺:胚細胞腫瘤 vs 體細胞腫瘤

AFP CD30 CD117 CK
Cocktail
EMA GPC-3 hCG hPL Inhibin
Seminoma +
Embryonal Carcinoma +
Choriocarcinoma + + + + +
Yolk Sac Tumor + + +
Somatic Carcinoma + +
Granulosa Cell Tumor +
Hypercalcaemic Small Cell Carcinoma + +

生殖腺:胚細胞腫瘤 vs 體細胞腫瘤 (part two)

43012 PLAP D2-40 Vimentin
Seminoma + + + +
Embryonal Carcinoma + +
Choriocarcinoma + -/+
Yolk Sac Tumor +
Somatic Carcinoma -/+
Granulosa Cell Tumor  +/- +
Hypercalcaemic Small Cell Carcinoma +

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頭部與頸部病理

副甲狀腺腫瘤 vs 甲狀腺腫瘤

Calcitonin PAX-8 Chromogranin
A
PTH S-100 Galectin-
3
Synaptophysin TTF-1
Parathyroid Tumors + + + +
Follicular Thyroid Tumors +  +/- + +
Medullary Thyroid Cacinoma + + + +

Back


 

血液病理

B細胞淋巴瘤

Annexin
AI
BCL2 BCL6 BOB.1 CDS CD10 CD11c CD20 CD23 CD25
Burkitt Lymphoma + + + +
CLL/SLL + -/+ + -/+ + +
Diffuse Large Cell Lymphoma +  +/- + -/+ +
Follicular + + + + +
Hairy Cell Leukemia + + + + +
Lymphoplasmacytic + + +
Malt Lymphoma + -/+ +
Mantle Cell + -/+ + + +
Marginal Zone + +
Marginal Zone BCL + -/+ +
Splenic Marginal Zone +

B細胞淋巴瘤 (part two)

CD43 CD45 CD79a Cyclin
D1
FoxP1 IgD Kappa Lambda MUM1 Octー2
Burkitt Lymphoma + + +  +/- -/+
CLL/SLL + + + +  +/- -/+ + +
Diffuse Large Cell Lymphoma + + +  +/- -/+  +/- +
Follicular + + +  +/- -/+ +
Hairy Cell Leukemia + +  +(weak)/-  +/- -/+  +(weak)/-
Lymphoplasmacytic + +  +/- -/+ +
Malt Lymphoma + +
Mantle Cell + + + + + -/+ -/+ +
Marginal Zone + + + + -/+ -/+ + +
Marginal Zone BCL + -/+ + +
Splenic Marginal Zone +  +/- +

B細胞淋巴瘤 (part three)

p27 PAX-5 PD-1 PU.1 TRAcP ZAP-70
Burkitt Lymphoma +
CLL/SLL + + +  +/-
Diffuse Large Cell Lymphoma + +
Follicular + + + +
Hairy Cell Leukemia + +
Lymphoplasmacytic +
Malt Lymphoma
Mantle Cell + + +
Marginal Zone + +  +/-
Marginal Zone BCL + + +  +/-
Splenic Marginal Zone

c-Myc (瀰漫大B細胞淋巴瘤)

BCL2 CD10 CD38 CD44 TCL1
Large B-cell Lymphoma with c-Myc Rearrangement -/+ + + +
Large B-cell Lymphoma with no c-Myc Rearrangement +  +/- + -/+

紅血球

CD71 Glycophorin
A
Hemoglobin
A
Spectrin
Erythroid Hyperplasia + + + +
Erythroid Hypoplasia + + + +
Acute Erythroid Leukemia + + + +
Extramedullary Hematopoiesis + + + +
Mature Erythrocytes + + +

組織球增生症

CD1a CD68 CD163 Factor
XIIIa
HAM-56 lysozyme S-100 Vimentin
Juvenile Xanthogranuloma + + + + + +
Langerhans Cell Histiocytosis + + + + + + +
Dermatofibroma + + +

霍奇金氏淋巴瘤(Hodgkin’s lymphoma) vs 非霍奇金氏淋巴瘤

EMA Fascin Granzyme
B
MUM1 Octー2 PU.1
Anaplastic Large Cell Lymphoma + +
Angioimmunoblastic T-cell Lymphoma
Hodgkin Lymphoma, Classic + +
Hodgkin Lymphoma, Nodular Lymphocyte Predominant + -/+ + +
T-cell Rich B-cell Lymphoma -/+ + +
T-cell Rich LBCL + +

免疫球蛋白(heavy chain、light chain)

IgA IgD IgG IgM Kappa Lambda
Cutaneous Lymphoma  +/- -/+
Myeloma + -/+ + -/+  +/- -/+
Diffuse LBCL + +  +/- -/+
Marginal Zone Lymphoma -/+ +  +/- -/+
SLL/CLL + +  +/- -/+

白血病

CD13 CD14 CD16 CD33 CD34 CD38 CD71 CD117 CD163 MPO
Acute Myeloid Leukemia with Minimal Differentiation + + + + + +
Acute Myeloid Leukemia without Maturation + + + + +
Acute Myeloid Leukemia with Maturation + + + + +
Acute Myelomonocytic Leukemia + + + +  +/- + + +
Acute Monoblastic and Monocytic Leukemia + + + + -/+  +/- + +
Acute Erythroid Leukemia -/+ +  +/-
Acute Megakaryoblastic Leukemia  +/-  +/-
Acute Basophilic Leukemia + +  +/-
Acute Panmyelosis with Myelofibrosis + + + +

淋巴結

CD1a CD14 CD21 CD35 CD68 CD163 Lysozyme PD-1 S-100
Reactive Histiocytosis + + +
Langerhans Cell Histiocytosis + + + + + +
Sinus Histiocytosis with Massive Lymphadenopathy + + + + +
Follicular Dendritic Cell Sarcoma  +/- + +
Dermatopathic Lymphadenitis + + + +

淋巴芽球性淋巴瘤 BCL vs TCL

CD1a CD3 CD5 CD7 CD10 CD19 CD20 CD74 CD117 PAX-5 TdT
Lymphoblastic BCL  +/- +  +/- + + +
Lymphoblastic TCL  +/- +  +/- + + +

淋巴瘤

CD3 CD20 CD43 CD45R CD45RO
Mature B-cell + +
Mature T-cell + + +

淋巴瘤(part two)

CD20 CD30 CD38 CD45 CD79a CD138 EMA HHV-8 MUM1 PAX-5
Plasmablastic Lymphoma + + + + + +
Primary Effusion Lymphoma  +/-  +/- + +  +/- + +
Large B-cell Lymphoma arising in HHV8-associated Multicentric Castleman Disease -/+ -/+ + + +
Extranodal Marginal Zone Lymphoma with Plasmacytoid Differentiation + + + +

淋巴瘤(part three)

Granzyme
B
Perforin TIA-1
NK/T Cell Lymphoma + + +
Hepatosplenic T-cell Lymphoma +
Cutaneous T-cell Lymphoma + + +
EBV+ Systemic T-lymphoproliferative Disorders + + +
T-cell Large Granular Lymphocytic Leukemia + + +
Adult T-cell Leukemia/Lymphoma
Marginal Zone
Marginal Zone BCL + + +

淋巴瘤(part four)

BCL2 BCL6 CD15 CD30 Cyclin
D1
Granzyme
B
IMP3 MUM1
Classical Hodgkin’s Lymphoma + + + + +
Lymphocyte Predominant Hodgkin Lymphoma + + + -/+

淋巴瘤(part five)

PAX-5 SOX-11
Classical Hodgkin’s Lymphoma +
Lymphocyte Predominant Hodgkin Lymphoma +

肥大細胞症

CD2 CD25 CD117 CD163 Tryptase
Mastocytosis / Systemic Mastocytosis + + + +
Mast Cell Leukemia + + + +
Reactive Mast Cells + + +

成熟B細胞淋巴瘤

Annexin
A1
BCL2 CD5 CD10 CD20 CD23 HGAL LMO2 Cyclin
D1
Follicular Lymphoma  +/-  +/- + + +
Diffuse Large B-cell Lymphoma + -/+  +/- + + +
Small Lymphocytic Lymphoma + + + +
Mantle Cell Lymphoma + + + +
Marginal Zone Lymphoma + +
Hairy Cell Leukemia + + +

成熟B細胞腫瘤

Annexin
A1
CD10 CD11c CD25 CD103 CD123 CyclinD1 DBA44 T-bet TRAcP
Hairy Cell Leukemia + + + + + +  +(weak)/-  +/- +  +/-
Hairy Cell Leukemia Variant +  +/-  +/-  +/-
Splenic Marginal Zone Lymphoma -/+  +/-  +/-

NK細胞 白血病/淋巴瘤

CD2 CD3 CD16 CD56 CD57 Granzyme
B
Perforin TIA-1
Aggressive NK-Cell Leukemia + + + + + + +
T-Cell Large Granular Lymphocytic Leukemia + + + + + + +
Extranodal NK/T-Cell Lymphoma, Nasal Type + + + + + +

非霍奇金氏淋巴瘤

CD5 CD10 CD20 CD23 Cyclin
D1
SOX-11
MCL + + + +
FL + +
SLL/CLL + + +
MZL +
LBL  +/- +
BL + -/+
CD5+ DLBCL + + +
Blastoid Variant MCL + + + +

漿細胞瘤與淋巴球增殖腫瘤

CD19 CD20 CD43 CD56 CD79a CD138 Cyclin
D1
EMA MUM1
Plasma Cell Neoplasm -/+ + + + -/+ + +
ALK + LBCL + + +
Plasmablastic Lymphoma + + + +
HHV Associated LBCL  +/-  +/-
Primary Effusion Lymphoma + + +
Lymphoblastic Lymphoma + + + +  +/-
Splenic Marginal Zone Lymphoma + + + -/+  +/-

脾造血増殖 Splenic Hematopoietic Proliferations

CD34 CD68 CD117 Hemoglobin
A
MPO
Chronic Myelogenous Leukemia -/+ +  +/- +
Chronic Idiopathic Myelofibrosis  +/- -/+ +
Myelodysplastic Syndrome + -/+
Myelodysplastic/Myeloproliferative Disorders + +
Mastocytosis + +
Erythroid Disorders +  +/-
Splenic Lymphoma -/+
Acute Myeloid Leukemia + + + +
Polycythemia Vera + + +

T細胞淋巴瘤

CD56 CD57 Granzyme
B
PD-1 Perforin TCL1
Angioimmunoblastic +
Lymphoblastic  +/-
Subcutaneous Panniculitis-Like + +
NK/T-cell Lymphoma +  +/- + + +
Cutaneous + -/+ +
Peripheral, NOS
Mycosis Fungoides  +/-

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神經病理

腦:CNS腫瘤1

EMA CK, pan GFAP Vimentin Olig2 S-100
Astrocytoma + +  +/- +
Oligodendrocytoma + +
Glioblastoma +  +/- + + +
Ependymoma +  +/- +
Meningloma +  +/- +  +/- -/+

腦:CNS腫瘤2

CK
Cocktail
EMA GFAP INI-1 NGFR Neurofilament PR S-100 Synaptophysin Vimentin
Astrocytoma + + + + +
Glioblastoma + + + +
Oligodendriglioma + + +
Ependymoma + + + +
Choroid Plexus Carcinoma + -/+ + + +  +/-
Central Neurocytoma + + +
Neuroblastoma  +/- + + + + -/+
Pineocytoma + + +
Meningloma + + + +
Schwannoma + + + + +
Rhabdoid Tumors + +  +/-  +/-  +/- +
Metastatic Carcinoma + + + -/+ -/+

透過組織學模仿腦膜瘤

ALDH1A1 CD34 Claudin-1 EMA E-cadherin GFAP S-100 STAT6
Meningothelial Meningioma + + +
Atypical Meningioma + + + +
Fibrous Meningioma + + +
Solitary Fibrous Tumor + + +
Meningeal Hemangiopericytoma + + -/+
Schwannoma  +/- + + +

腹膜後腫瘤

CD99 Chromogranin
A
GFAP MBP Neurofilament NSE PGP 9.5 S-100 Synaptophysin
Neuroblastoma +  +/- + + + +
Ganglioneuroblastoma + + -/+ + + + + +
Ganglioneuroma + + + + + + + +

Back


 

小兒科病理

組織球増殖

CD1a CD68 CD163 Factor
XIIIa
HAM-56 Lysozyme S-100 Vimentin
Juvenile Xanthogranuloma + + + + + +
Langerhans Cell Histiocytosis + + + + + + +
Dermatofibroma + + +

腹膜後病變

Chromogranin
A
CD99 GFAP Neurofilament NSE PGP 9.5 S-100 Synaptophysin
Neuroblastoma + -/+ + + + +
Ganglioneuroblastoma + + + + + + +
Ganglioneuroma + + + + + + +
Leiomyosarcoma -/+ -/+
Rhabdomyosarcoma +
Synovial Sarcoma  +/- -/+

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肺病理

肺腺癌 vs 間皮瘤

BGB Caldesmon Calretinin CEA CK 5&6 Ber-EP4
Adenocarcinoma + + +
Mesothelioma + + +

肺腺癌 vs 間皮瘤 (part two)

E-cadherin HBME-1 D2-40 TAG-72 TTF-1
Adenocarcinoma + + +
Mesothelioma + +

肺扁平上皮癌 vs 腺癌

CK 5&6 Desmocollin3 Napsin
A
p63 SOX-2 TTF-1
Lung Adenocarcinoma + -/+ -/+ +
Lung Squamous Cell Carcinoma + + + +

胸膜: 肺腺癌 vs 間皮瘤

Caldesmon Calretinin CEA CK 5 CK 5&6 Ep-CAM E-cadherin HBME-1 Napsin
A
D2-40
Adenocarcinoma + + + +
Mesothelioma + + + + + +

胸膜: 肺腺癌 vs 間皮瘤 (part two)

TAG-72 TTF-1 TBM WT1
Adenocarcinoma + +
Mesothelioma + +

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軟部組織病理

組織球性細胞損傷/樹狀細胞損傷

CD1a CD21 CD23 CD35 CD68 CD163 Langerin Lysozyme S-100
Langerhans Cell Histiocytosis + + + +  +/- +
Rosai-Dorfman Disease + + + +
Follicular Dendritic Cell Sarcoma + + +  +/-  +/-
Interdigitating Dendritic Cell Sarcoma  +/- + + +
Histiocytic Sarcoma + + +  +/-
Juvenile Disseminated Xanthogranuloma + + +  +/-

惡性肌肉腫瘤

SM
Actin
MS
Actin
Myogenin PGP 9.5 Caldesmon Myoglobin Calponin Vimentin INI-1
Leiomyosarcoma + + + + +
Rhabdomyosarcoma -/+ -/+ + + + + +

小圓細胞腫瘤

MS
Actin
SM
Actin
Caldesmon Calponin CD45 CD57 CD99 CK
Cocktail
FLI-1
Lymphoblastic Lymphoma + + +
Leiomyosarcoma + + + +  +/- -/+
Rhabdomyosarcoma
Neuroblastoma +
Embryonal Carcinoma + +
PNET/ES + + -/+ +
DSRCT  +/- + +
Medulloblastoma +

小圓細胞腫瘤 (part two)

INI-1 Myogenin Myoglobin PGP 9.5 Vimentin WT1
Lymphoblastic Lymphoma + +
Leiomyosarcoma +
Rhabdomyosarcoma + + + + +
Neuroblastoma + + +
Embryonal Carcinoma + +
PNET/ES + + +
DSRCT + + +
Medulloblastoma +

軟部組織衍生物

MS
Actin
SM
Actin
Calretinin CD34 CD56 CK
Cocktail
Desmin HMB-45 S-100 TFE3
Alveolar Soft Part Sarcoma + + +
Clear Cell Sarcoma + +
Leiomyosarcoma + + -/+ + -/+ +
PEComa + + + + +

軟部組織肉瘤

MS
Actin
SM
Actin
Calponin Calretinin CD34 CD56 CD99 CK
Cocktail
Desmin EMA
Alveolar Soft Part Sarcoma + +
Clear Cell Sarcoma
Desmoplastic Small Round Cell +
Epithelioid Sarcoma -/+ + + +
Leiomyosarcoma + + -/+ + -/+ + -/+
Mesenchymal Chondrosarcoma + -/+ +
Myxoid Chondrosarcoma  +/- + -/+
PEComa + +
PNET/ES + -/+
Rhabdomyosarcoma -/+ -/+ + +
Synovial Sarcoma  +/- + + + +

軟部組織肉瘤 (part two)

Myogenin S-100 TFE3 TLE1
Alveolar Soft Part Sarcoma +
Clear Cell Sarcoma +
Desmoplastic Small Round Cell
Epithelioid Sarcoma
Leiomyosarcoma
Mesenchymal Chondrosarcoma  +/-
Myxoid Chondrosarcoma
PEComa
PNET/ES +
Rhabdomyosarcoma +
Synovial Sarcoma -/+ +

軟部組織腫瘤

MS
Actin
SM
Actin
ALK Calponin CD34 CD99 CK
Cocktail
Desmin EMA FLI-1
Alveolar Soft Part Sarcoma + +
Clear Cell Sarcoma
Desmoplastic Small Round Cell + +
Epithelioid Sarcoma -/+ + + +
Fibrous Histiocytoma +
Inflammatory Myo broblastic Tumor + + +
Leiomyosarcoma + + + -/+
Myxoid Chondrosarcoma -/+
PEComa +  +/-
PNET/ES + -/+ +
Rhabdomyosarcoma -/+ -/+
Synovial Sarcoma + + +

軟部組織腫瘤 (part two)

INI-1 Myogenin PGP 9.5 S-100 TFE3 TLE1
Alveolar Soft Part Sarcoma +
Clear Cell Sarcoma +
Desmoplastic Small Round Cell
Epithelioid Sarcoma
Fibrous Histiocytoma
Inflammatory Myo broblastic Tumor
Leiomyosarcoma
Myxoid Chondrosarcoma  +/-
PEComa
PNET/ES + + +
Rhabdomyosarcoma + + +
Synovial Sarcoma +

血管腫瘤

CD34 ERG Factor
VIII
FLI-1 HHV-8 D2-40
Hemangioma + + + +
Kaposi’s Sarcoma + + + + + +
Hemangioendothelioma + + +
Angiosarcoma + + + +  +/-
Colorectal Adenocarcinoma -/+
Invasive Ductal Carcinoma -/+

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